Population structure among study subjects may confound genetic association studies, and lack of proper correction can lead to spurious findings. Assessing ancestry-based adjustments in GTEx improves portability of this research across populations and further characterizes the impact of population structure on GWAS colocalization. Here, we identify a subset of individuals in GTEx v8 with a high degree of population admixture and estimate genome-wide local ancestry. We perform genome-wide cis-eQTL mapping using admixed samples in seven tissues, adjusted by either global or local ancestry. Consistent with previous work, we observe improved power with local ancestry adjustment. At loci where the two adjustments produce different lead variants, we observe 31 loci 0.
Nicole Gay's Profile | Stanford Profiles
By Daniel Megarry. Did you have any idea that Nailed It! No, I had no idea! I mean, those Donald Trump cakes were pretty horrific, but I also truly love them. Do you find it hard to walk that line between throwing a bit of shade and being downright mean? It is a fine line to walk.
Nicole took care of a woman that came from a nursing home and was in pretty bad shape. She was a sick lady. Nicole started getting to know this lady and discovered that both she and the patient were avid book readers.
Nicole Ellis is the former next door neighbor of the Huangs and Eddie Huang 's former love interest. She made her first appearance in " The Shunning ". She is portrayed by Luna Blaise. Nicole made her first appearance at the end of the episode " The Shunning ". Shortly after Eddie had finally hugged Honey, he saw Nicole step out of the car and he immediately fell in love with her.